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Natrium-Zirkonium-Cyclosilikat ist ein Ilokelma wirkstoffonenaustauscher zur Behandlung einer Hyperkaliämie. Es wird als Lokelma® unter dem Handelsnamen vertrieben und hat einen Zusatznutzen, der nicht belegt ist.

Lokelma is indicated for the treatment of hyperkalaemia in adult patients (see section 4.4 and 5.1). Correction phase The recommended starting dose of Lokelma is 10 g, administered three。

Lokelma 10 g administered three times daily lowered serum potassium by -0.7 mmol/L at 48 hours (p < 0.001 vs. placebo); statistically significant 14% potassium reduction was observed 1 hour after the first dose. Patients with higher startinlokelma wirkstoffg。

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